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One of the most serious problems currently affecting agricultural productivity in developing countries of the tropics, including Nigeria, is land degradation. This study assessed the farmers’ perception of the effects of land degradation on agricultural activities in Ethiopia East LGA of Delta State. A multi-stage sampling technique was used in the selection of the respondents. A total of 60 farmers were randomly selected through the use of structured interview schedule. The data were analyzed using frequency, percentage and mean statistic. The results of the study revealed that, the major causes of land degradation as perceived by the farmers in the area included: accelerated erosion ( x =1.87), deforestation ( x =1.72), non-adoption of adequate soil conservation measures ( x =1.37), administrative and institutional problems ( x =1.70) and exploration of crude oil ( x =1.70). The perceived major effects of land degradation on agricultural production were: decrease in farm land available for cultivation ( x =3.85), reduction in farm yields/output ( =3.82) and loss of nutrients/ organic matter ( x =3.81). To restore, sustain and enhance the productive and protective functions of the land in the area, the study recommended soil productivity restoration approaches {application of manure ( x =2.00), mixed cropping ( x =1.92), crop rotation ( x =1.18)} and effective stakeholders participation in land use planning and management ( x =1.78).