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The goal of this study is to propose a new classification of African ecosystems based on an 8-year analysis of Normalized Difference Vegetation Index (NDVI) data sets from SPOT/VEGETATION. We develop two methods of classification. The first method is obtained from a k-nearest neighbour (k-NN) classifier, which represents a simple machine learning algorithm in pattern recognition. The second method is hybrid in that it combines k-NN clustering, hierarchical principles and the Fast Fourier Transform (FFT). The nomenclature of the two classifications relies on three levels of vegetation structural categories based on the Land Cover Classification System (LCCS). The two main outcomes are: (i) The delineation of the spatial distribution of ecosystems into five bioclimatic ecoregions at the African continental scale; (ii) Two ecosystem maps were made sequentially: an initial map with 92 ecosystems from the k-NN, plus a deduced hybrid classification with 73 classes, which better reflects the bio-geographical patterns. The inclusion of bioclimatic information and successive k-NN clustering elements helps to enhance the discrimination of ecosystems. Adopting this hybrid approach makes the ecosystem identification and labelling more flexible and more accurate in comparison to straightforward methods of classification. The validation of the hybrid classification, conducted by crossing-comparisons with validated continental maps, displayed a mapping accuracy of 54% to 61%.