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This policy brief discusses the issue of food security in relation to trade and the anticipated impacts of climate change within Southeast Asia. It begins by contextualizing the debate before examining the manner in which trade, climate change and food security are interlinked within the Mekong region. The brief goes onto examine Cambodia as a case study in order to establish lessons for other countries in the region. The document ends with a series of policy recommendations drawn from the experience of Cambodia; these include: a call for a more holistic approach that links policymakers operating in different sectors, a greater degree of participation by actors at the local level and by civil society organizations, a stronger and more long-term vision and an enhanced degree of regional coordination.